Induction of autophagy through the activating transcription factor 4 (ATF4)-dependent amino acid response pathway in maternal skeletal muscle may function as the molecular memory in response to gestational protein restriction to alert offspring to maternal nutrition.

Wang, Huan; Wilson, Gabriel J; Zhou, Dan; Lezmi, Stéphane; Chen, Xiuwen; Layman, Donald K; Pan, Yuan-Xiang

Wang, Huan; Wilson, Gabriel J; Zhou, Dan; Lezmi, Stéphane; Chen, Xiuwen; Layman, Donald K; Pan, Yuan-Xiang.

Afiliação

Wang H; Department of Food Science and Human Nutrition,College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Wilson GJ; Division of Nutritional Sciences, College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Zhou D; Department of Food Science and Human Nutrition,College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Lezmi S; Division of Nutritional Sciences, College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Chen X; Department of Food Science and Human Nutrition,College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Layman DK; Department of Food Science and Human Nutrition,College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.
Pan YX; Department of Food Science and Human Nutrition,College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign,905 South Goodwin Avenue,Urbana,IL61801,USA.

Br J Nutr ; 114(4): 519-32, 2015 Aug 28.

Article em En | MEDLINE | ID: mdl-26198178

Assuntos

Fator 4 Ativador da Transcrição/metabolismo; Aminoácidos/metabolismo; Autofagia; Dieta com Restrição de Proteínas; Proteínas Alimentares/administração & dosagem; Músculo Esquelético/metabolismo; Fenômenos Fisiológicos da Nutrição Pré-Natal; Animais; Autofagia/genética; Proteínas Alimentares/farmacologia; Ingestão de Energia; Fatores de Iniciação em Eucariotos/metabolismo; Feminino; Masculino; Memória; Proteínas Associadas aos Microtúbulos/metabolismo; Gravidez; RNA Mensageiro/metabolismo; Ratos Sprague-Dawley

Palavras-chave

Autophagy; Genes; Pregnancy; Protein restriction; Transcription factors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Proteínas Alimentares / Músculo Esquelético / Dieta com Restrição de Proteínas / Fenômenos Fisiológicos da Nutrição Pré-Natal / Fator 4 Ativador da Transcrição / Aminoácidos Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Br J Nutr Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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