Endocannabinoids and Mental Disorders.
Handb Exp Pharmacol
; 231: 261-83, 2015.
Article
em En
| MEDLINE
| ID: mdl-26408164
ABSTRACT
Preclinical and clinical data fully support the involvement of the endocannabinoid system in the etiopathogenesis of several mental diseases. In this review we will briefly summarize the most common alterations in the endocannabinoid system, in terms of cannabinoid receptors and endocannabinoid levels, present in mood disorders (anxiety, posttraumatic stress disorder, depression, bipolar disorder, and suicidality) as well as psychosis (schizophrenia) and autism. The arising picture for each pathology is not always straightforward; however, both animal and human studies seem to suggest that pharmacological modulation of this system might represent a novel approach for treatment.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Transtorno Autístico
/
Encéfalo
/
Transtornos do Humor
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Endocanabinoides
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Handb Exp Pharmacol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Itália