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NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance.
Li, Feng; He, Xiadi; Ye, Dingwei; Lin, Yan; Yu, Hongxiu; Yao, Cuifang; Huang, Lei; Zhang, Jianong; Wang, Fang; Xu, Sha; Wu, Xiaohui; Liu, Lixia; Yang, Chen; Shi, Jiaqi; He, Xiaoyang; Liu, Jie; Qu, Yuanyuan; Guo, Fushen; Zhao, Jianyuan; Xu, Wei; Zhao, Shimin.
Afiliação
  • Li F; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; State Key Laboratory of Biotherapy/Collaborative Innovation Center f
  • He X; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai 200032, P.R. China; State Key Lab
  • Ye D; Department of Urology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, P.R. China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
  • Lin Y; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; State Key Laboratory of Biotherapy/Collaborative Innovation Center f
  • Yu H; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.
  • Yao C; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.
  • Huang L; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai 200032, P.R. China.
  • Zhang J; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai 200032, P.R. China.
  • Wang F; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.
  • Xu S; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China.
  • Wu X; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institute of Developmental Biology and Molecular Medicine, Fudan University, Shanghai 200032, P.R. China.
  • Liu L; Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, P.R. China.
  • Yang C; Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, P.R. China.
  • Shi J; Department of Urology, Affiliated Hospital of Guiyang Medical College, Guiyang 550004, P.R. China.
  • He X; Guizhou Cancer Hospital, Guiyang 550001, P.R. China.
  • Liu J; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; Institute of Digestive Medicine, Affiliated Huashan Hospital, Fudan University, Shanghai 200032, P.R. China; Department of Urology, Affiliated Hospital of Guiyang Medical College, Guiyang 550004, P.R. China.
  • Qu Y; Department of Urology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai 200032, P.R. China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China.
  • Guo F; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Gene
  • Zhao J; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Genetics and Development, Fudan University, Shanghai 200032, P.R. China.
  • Xu W; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; State Key Laboratory of Biotherapy/Collaborative Innovation Center f
  • Zhao S; State Key Lab of Genetic Engineering and the Obstetrics & Gynecology Hospital of Fudan University, Fudan University, Shanghai 200032, P.R. China; Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, P.R. China; School of Life Sciences and Collaborative Innovation Center for Gene
Mol Cell ; 60(4): 661-75, 2015 Nov 19.
Article em En | MEDLINE | ID: mdl-26585387
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Succínico / Glutaratos / Isocitrato Desidrogenase / Mitocôndrias / Mutação / Neoplasias Experimentais Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Succínico / Glutaratos / Isocitrato Desidrogenase / Mitocôndrias / Mutação / Neoplasias Experimentais Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2015 Tipo de documento: Article