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Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
Hudson, William H; Kossmann, Bradley R; de Vera, Ian Mitchelle S; Chuo, Shih-Wei; Weikum, Emily R; Eick, Geeta N; Thornton, Joseph W; Ivanov, Ivaylo N; Kojetin, Douglas J; Ortlund, Eric A.
Afiliação
  • Hudson WH; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322;
  • Kossmann BR; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;
  • de Vera IM; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL 33458;
  • Chuo SW; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;
  • Weikum ER; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322;
  • Eick GN; Institute of Ecology and Evolution, University of Oregon, Eugene, OR 97403;
  • Thornton JW; Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637; Department of Human Genetics, University of Chicago, Chicago, IL 60637.
  • Ivanov IN; Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30302;
  • Kojetin DJ; Department of Molecular Therapeutics, The Scripps Research Institute, Scripps Florida, Jupiter, FL 33458;
  • Ortlund EA; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322; eric.ortlund@emory.edu.
Proc Natl Acad Sci U S A ; 113(2): 326-31, 2016 Jan 12.
Article em En | MEDLINE | ID: mdl-26715749
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / DNA / Homologia de Sequência de Aminoácidos Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / DNA / Homologia de Sequência de Aminoácidos Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2016 Tipo de documento: Article