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Cyclophosphamide treatment-induced leukopenia rates in ANCA-associated vasculitis are influenced by variant CYP450 2C9 genotypes.
Schirmer, Jan Henrik; Bremer, Jan Phillip; Moosig, Frank; Holle, Julia Ulrike; Lamprecht, Peter; Wieczorek, Stefan; Haenisch, Sierk; Cascorbi, Ingolf.
Afiliação
  • Schirmer JH; Department of Rheumatology & Clinical Immunology, Vasculitis Center, University Hospital Schleswig-Holstein & Klinkum Bad Bramstedt, Bad Bramstedt, Germany.
  • Bremer JP; Department of Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Moosig F; Department of Rheumatology & Clinical Immunology, Vasculitis Center, University Hospital Schleswig-Holstein & Klinkum Bad Bramstedt, Bad Bramstedt, Germany.
  • Holle JU; Department of Rheumatology & Clinical Immunology, Vasculitis Center, University Hospital Schleswig-Holstein & Klinkum Bad Bramstedt, Bad Bramstedt, Germany.
  • Lamprecht P; Department of Rheumatology & Clinical Immunology, Vasculitis Center, University Hospital Schleswig-Holstein & Klinkum Bad Bramstedt, Bad Bramstedt, Germany.
  • Wieczorek S; Department of Rheumatology & Comprehensive Center for Inflammation Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.
  • Haenisch S; Human Genetics, Ruhr University Bochum, Bochum, Germany.
  • Cascorbi I; Institute for Experimental & Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Pharmacogenomics ; 17(4): 367-74, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26894931
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciclofosfamida / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Citocromo P-450 CYP2C9 / Imunossupressores / Leucopenia Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics Assunto da revista: FARMACOLOGIA / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciclofosfamida / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Citocromo P-450 CYP2C9 / Imunossupressores / Leucopenia Tipo de estudo: Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics Assunto da revista: FARMACOLOGIA / GENETICA MEDICA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Alemanha