Your browser doesn't support javascript.
loading
Chemoenzymatic synthesis of enantiopure hydroxy sulfoxides derived from substituted arenes.
Boyd, Derek R; Sharma, Narain D; Malone, John F; Ljubez, Vera; Murphy, Deirdre; Shepherd, Steven D; Allen, Christopher C R.
Afiliação
  • Boyd DR; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Sharma ND; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Malone JF; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Ljubez V; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Murphy D; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Shepherd SD; School of Chemistry and Chemical Engineering, Queen's University, Belfast BT9 5AG, UK. dr.boyd@qub.ac.uk.
  • Allen CC; School of Biological Sciences, Queen's University of Belfast, Belfast, BT9 5AG, UK.
Org Biomol Chem ; 14(9): 2651-64, 2016 Mar 07.
Article em En | MEDLINE | ID: mdl-26907786
Enantiopure ß-hydroxy sulfoxides and catechol sulfoxides were obtained, by chemoenzymatic synthesis, involving dioxygenase-catalysed benzylic hydroxylation or arene cis-dihydroxylation and cis-diol dehydrogenase-catalysed dehydrogenation. Absolute configurations of chiral hydroxy sulfoxides were determined by X-ray crystallography, ECD spectroscopy and stereochemical correlation. The application of a new range of ß-hydroxy sulfoxides as chiral ligands was examined.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfóxidos / Dioxigenases Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfóxidos / Dioxigenases Idioma: En Revista: Org Biomol Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2016 Tipo de documento: Article