Clinical and cognitive insight in patients with acute-phase psychosis: Association with treatment and neuropsychological functioning.
Nord J Psychiatry
; 70(7): 528-35, 2016 Oct.
Article
em En
| MEDLINE
| ID: mdl-27116999
ABSTRACT
BACKGROUND:
The severity of psychopathology cannot fully explain deficits in the multi-dimensional construct of insight.AIMS:
The aim of this study was to evaluate the correlates and associations of clinical and cognitive insight in patients in an acute phase of psychosis and to analyse the impact of acute treatment on these variables.METHODS:
This study examined 47 inpatients who were recently hospitalized with acute exacerbation of schizophrenia. All subjects were assessed at both admission and discharge with the Positive and Negative Syndrome Scale (PANSS), Schedule for the Assessment of Insight-Expanded Version (SAI-E), Beck Cognitive Insight Scale (BCIS), and a neurocognition battery.RESULTS:
Patients with schizophrenia gained clinical insight after treatment. Cognitive insight did not change significantly after treatment. Insight showed significant negative correlations with positive symptoms and general psychopathology, but not with negative symptoms. Clinical insight was not associated with neuropsychological functioning in this cohort.CONCLUSION:
Gaining clinical insight in the acute phase of illness was associated with the remission of positive symptoms, but not with neuropsychological functioning. Some significant correlations between clinical and cognitive insights were detected, which suggests that cognitive insight contributes to clinical insight but is not treatment-dependent. Long-term treatment may be required to understand the contribution of insight to the outcome of patients with schizophrenia.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Psicóticos
/
Esquizofrenia
/
Avaliação de Resultados em Cuidados de Saúde
/
Teoria da Mente
/
Metacognição
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Nord J Psychiatry
Assunto da revista:
PSICOFARMACOLOGIA
/
PSIQUIATRIA
Ano de publicação:
2016
Tipo de documento:
Article