Conformational selection in amyloid-based immunotherapy: Survey of crystal structures of antibody-amyloid complexes.

Ma, Buyong; Zhao, Jun; Nussinov, Ruth

Ma, Buyong; Zhao, Jun; Nussinov, Ruth.

Afiliação

Ma B; Basic Science Program, Leidos Biomedical Research, Inc., Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, United States. Electronic address: mabuyong@mail.nih.gov.
Zhao J; Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, United States.
Nussinov R; Basic Science Program, Leidos Biomedical Research, Inc., Cancer and Inflammation Program, National Cancer Institute, Frederick, MD 21702, United States; Sackler Inst. of Molecular Medicine, Department of Human Genetics and Molecular Medicine Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.

Biochim Biophys Acta ; 1860(11 Pt B): 2672-81, 2016 11.

Article em En | MEDLINE | ID: mdl-27266343

Assuntos

Amiloide/química; Anticorpos/química; Sequência de Aminoácidos; Amiloide/metabolismo; Anticorpos/metabolismo; Humanos; Imunoterapia/métodos; Doenças Neurodegenerativas/metabolismo; Conformação Proteica

Palavras-chave

Alzheimer's disease; Amyloid; Antibody; Antigen; Biological drug; Neurodegenerative diseases; Prion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Amiloide / Anticorpos Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2016 Tipo de documento: Article

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