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An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria.
Liebow, Abigail; Li, Xingsheng; Racie, Timothy; Hettinger, Julia; Bettencourt, Brian R; Najafian, Nader; Haslett, Patrick; Fitzgerald, Kevin; Holmes, Ross P; Erbe, David; Querbes, William; Knight, John.
Afiliação
  • Liebow A; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and aliebow@alnylam.com.
  • Li X; Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama.
  • Racie T; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Hettinger J; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Bettencourt BR; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Najafian N; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Haslett P; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Fitzgerald K; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Holmes RP; Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama.
  • Erbe D; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Querbes W; Alnylam Pharmaceuticals, Departments of Research and Development, Cambridge, Massachusetts; and.
  • Knight J; Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama.
J Am Soc Nephrol ; 28(2): 494-503, 2017 02.
Article em En | MEDLINE | ID: mdl-27432743
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxalatos / Hiperoxalúria Primária / Oxirredutases do Álcool / Terapêutica com RNAi Limite: Animals Idioma: En Revista: J Am Soc Nephrol Assunto da revista: NEFROLOGIA Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxalatos / Hiperoxalúria Primária / Oxirredutases do Álcool / Terapêutica com RNAi Limite: Animals Idioma: En Revista: J Am Soc Nephrol Assunto da revista: NEFROLOGIA Ano de publicação: 2017 Tipo de documento: Article