MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects.

Urner-Bloch, U; Urner, M; Jaberg-Bentele, N; Frauchiger, A L; Dummer, R; Goldinger, S M

MEK inhibitor-associated retinopathy (MEKAR) in metastatic melanoma: Long-term ophthalmic effects.

Urner-Bloch, U; Urner, M; Jaberg-Bentele, N; Frauchiger, A L; Dummer, R; Goldinger, S M.

Afiliação

Urner-Bloch U; Private Ophthalmic Practice in Cooperation with the Skin Cancer Unit, University Hospital of Zurich, Zurich, Switzerland.
Urner M; Medical Intensive Care Unit, University Hospital Zurich, Zurich, Switzerland; Institute of Physiology, University of Zurich, Zurich, Switzerland.
Jaberg-Bentele N; Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
Frauchiger AL; Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
Dummer R; Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland. Electronic address: reinhard.dummer@usz.ch.
Goldinger SM; Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.

Eur J Cancer ; 65: 130-8, 2016 09.

Article em En | MEDLINE | ID: mdl-27497344

Assuntos

Antineoplásicos/efeitos adversos; Benzimidazóis/efeitos adversos; Melanoma; Quinases de Proteína Quinase Ativadas por Mitógeno/antagonistas & inibidores; Inibidores de Proteínas Quinases/efeitos adversos; Proteínas Proto-Oncogênicas B-raf/antagonistas & inibidores; Doenças Retinianas/induzido quimicamente; Idoso; Relação Dose-Resposta a Droga; Feminino; Humanos; Masculino; Melanoma/tratamento farmacológico; Melanoma/genética; Melanoma/secundário; Pessoa de Meia-Idade; Estudos Prospectivos; Neoplasias Cutâneas/genética

Palavras-chave

BRAF inhibition; Long-term treatment; MEK inhibition; Melanoma; Optical coherence tomography; Retinopathy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Benzimidazóis / Quinases de Proteína Quinase Ativadas por Mitógeno / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases / Melanoma / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suíça

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