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Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis.
Li, Yinyin; Shen, Yi; Hohensinner, Philipp; Ju, Jihang; Wen, Zhenke; Goodman, Stuart B; Zhang, Hui; Goronzy, Jörg J; Weyand, Cornelia M.
Afiliação
  • Li Y; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Shen Y; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Hohensinner P; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Internal Medicine II/Cardiology, Medical University of Vienna, 1090 Vienna, Austria.
  • Ju J; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Wen Z; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Goodman SB; Department of Orthopedic Surgery and Bioengineering, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Zhang H; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Goronzy JJ; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Weyand CM; Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: cweyand@stanford.edu.
Immunity ; 45(4): 903-916, 2016 10 18.
Article em En | MEDLINE | ID: mdl-27742546
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Linfócitos T / Senescência Celular / Desoxirribonucleases / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Linfócitos T / Senescência Celular / Desoxirribonucleases / Proteínas de Ligação a DNA Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos