Dermal Titanium Dioxide Deposition Associated With Intralesional Triamcinolone Injection.
Am J Dermatopathol
; 38(12): e163-e166, 2016 Dec.
Article
em En
| MEDLINE
| ID: mdl-27861183
ABSTRACT
Cutaneous discoloration secondary to dermal deposition of titanium dioxide (TiO2) particles is recognized but seldom reported in the literature. In this report, the authors describe the case of a 61-year-old gentleman, with a long history of alopecia areata, who presented with numerous, discrete dark blue macules on the scalp. Scanning electron microscopy with energy dispersive x-ray spectroscopy analysis ultimately identified the macules as deposits of TiO2. The patient had a history of intralesional triamcinolone injections for management of alopecia areata. A sample of generic 0.1% triamcinolone acetonide paste was analyzed and found to contain many TiO2 particles analogous to those seen in the patient's biopsy sample. To the authors' knowledge, this is the first reported case of TiO2 deposition in the dermis likely resulting from topical combined with intralesional triamcinolone injection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Couro Cabeludo
/
Pele
/
Titânio
/
Triancinolona Acetonida
/
Alopecia em Áreas
/
Glucocorticoides
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Middle aged
Idioma:
En
Revista:
Am J Dermatopathol
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Canadá