Specific stabilization of CFTR by phosphatidylserine.

Hildebrandt, Ellen; Khazanov, Netaly; Kappes, John C; Dai, Qun; Senderowitz, Hanoch; Urbatsch, Ina L

Hildebrandt, Ellen; Khazanov, Netaly; Kappes, John C; Dai, Qun; Senderowitz, Hanoch; Urbatsch, Ina L.

Afiliação

Hildebrandt E; Department of Cell Biology and Biochemistry, and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX 79430, USA. Electronic address: ellen.hildebrandt@ttuhsc.edu.
Khazanov N; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel. Electronic address: netalyk@gmail.com.
Kappes JC; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA; Birmingham Veterans Medical Center, Research Service, Birmingham, AL 35233, USA. Electronic address: kappesjc@uab.edu.
Dai Q; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA. Electronic address: daiq@uab.edu.
Senderowitz H; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel. Electronic address: hanoch@biu.ac.il.
Urbatsch IL; Department of Cell Biology and Biochemistry, and Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX 79430, USA. Electronic address: ina.urbatsch@ttuhsc.edu.

Biochim Biophys Acta Biomembr ; 1859(2): 289-293, 2017 Feb.

Article em En | MEDLINE | ID: mdl-27913277

Assuntos

Regulador de Condutância Transmembrana em Fibrose Cística/metabolismo; Fosfatidilserinas/metabolismo; Transportadores de Cassetes de Ligação de ATP/metabolismo; Adenosina Trifosfatases; Trifosfato de Adenosina/metabolismo; Sítios de Ligação/fisiologia; Linhagem Celular; Membrana Celular/metabolismo; Regulador de Condutância Transmembrana em Fibrose Cística/genética; Humanos; Hidrólise; Mutação/genética; Nucleotídeos/metabolismo; Ligação Proteica/fisiologia

Palavras-chave

ABC transporters; ATP hydrolysis; Blind docking; Cystic Fibrosis Transmembrane Conductance Regulator; Phosphatidylserine; Thermal stability

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidilserinas / Regulador de Condutância Transmembrana em Fibrose Cística Limite: Humans Idioma: En Revista: Biochim Biophys Acta Biomembr Ano de publicação: 2017 Tipo de documento: Article

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