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The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells.
Dyshlovoy, Sergey A; Madanchi, Ramin; Hauschild, Jessica; Otte, Katharina; Alsdorf, Winfried H; Schumacher, Udo; Kalinin, Vladimir I; Silchenko, Alexandra S; Avilov, Sergey A; Honecker, Friedemann; Stonik, Valentin A; Bokemeyer, Carsten; von Amsberg, Gunhild.
Afiliação
  • Dyshlovoy SA; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany. dyshlovoy@gmail.com.
  • Madanchi R; Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences, Prospekt 100-let Vladivostoku 159, Vladivostok, 690022, Russian Federation. dyshlovoy@gmail.com.
  • Hauschild J; School of Natural Sciences, Far Eastern Federal University, Sukhanova Street 8, Vladivostok, 690091, Russian Federation. dyshlovoy@gmail.com.
  • Otte K; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Alsdorf WH; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Schumacher U; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Kalinin VI; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Silchenko AS; Institute of Anatomy and Experimental Morphology, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Avilov SA; Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences, Prospekt 100-let Vladivostoku 159, Vladivostok, 690022, Russian Federation.
  • Honecker F; Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences, Prospekt 100-let Vladivostoku 159, Vladivostok, 690022, Russian Federation.
  • Stonik VA; Laboratory of Experimental Oncology, Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, 20246, Germany.
  • Bokemeyer C; Laboratory of Marine Natural Products Chemistry, G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-East Branch, Russian Academy of Sciences, Prospekt 100-let Vladivostoku 159, Vladivostok, 690022, Russian Federation.
  • von Amsberg G; School of Natural Sciences, Far Eastern Federal University, Sukhanova Street 8, Vladivostok, 690091, Russian Federation.
BMC Cancer ; 17(1): 93, 2017 02 01.
Article em En | MEDLINE | ID: mdl-28143426

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Triterpenos / Apoptose / Glicosídeos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Triterpenos / Apoptose / Glicosídeos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: BMC Cancer Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha