Controlled ovarian stimulation and triggers in in vitro fertilization: protocol personalization key to optimize outcomes.
Minerva Endocrinol
; 43(1): 37-49, 2018 Mar.
Article
em En
| MEDLINE
| ID: mdl-28322538
ABSTRACT
The past four decades have delivered many advancements to improve in vitro fertilization (IVF) outcomes. These include a delicate balance of controlled ovarian hyperstimulation (COH) without causing ovarian hyperstimulation syndrome (OHSS), a safe oocyte retrieval, fertilization and embryo culture, endometrial growth and receptivity to promote implantation, and luteal support to maintain the pregnancy. Contemporary IVF practice includes both the classic COH protocols as well as protocols for poor responders and those for specific patient populations. An assortment of agents have been developed and utilized in various combinations to improve COH outcomes and promote oocyte maturation while decreasing the risk of OHSS. Various protocols have evolved over time. Ideal practices involve selecting the optimal protocol for a personalized, patient-specific stimulation and trigger.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Indução da Ovulação
/
Fertilização in vitro
/
Medicina de Precisão
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Pregnancy
Idioma:
En
Revista:
Minerva Endocrinol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos