Tetraspanins in infections by human cytomegalo- and papillomaviruses.

Fast, Laura A; Lieber, Diana; Lang, Thorsten; Florin, Luise

Fast, Laura A; Lieber, Diana; Lang, Thorsten; Florin, Luise.

Afiliação

Fast LA; Department of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Lieber D; Institute of Virology, Ulm University Medical Center, Ulm, Germany.
Lang T; Department of Membrane Biochemistry, Life & Medical Sciences Institute, University of Bonn, Bonn, Germany.
Florin L; Department of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg University, Mainz, Germany lflorin@uni-mainz.de.

Biochem Soc Trans ; 45(2): 489-497, 2017 04 15.

Article em En | MEDLINE | ID: mdl-28408489

ABSTRACT

ABSTRACT

Members of the tetraspanin family have been identified as essential cellular membrane proteins in infectious diseases by nearly all types of pathogens. The present review highlights recently published data on the role of tetraspanin CD151, CD81, and CD63 and their interaction partners in host cell entry by human cytomegalo- and human papillomaviruses. Moreover, we discuss a model for tetraspanin assembly into trafficking platforms at the plasma membrane. These platforms might persist during intracellular viral trafficking.

Assuntos

Infecções por Citomegalovirus/metabolismo; Infecções por Papillomavirus/metabolismo; Tetraspaninas/metabolismo; Proteínas Virais/metabolismo; Membrana Celular/metabolismo; Citomegalovirus/fisiologia; Humanos; Modelos Moleculares; Papillomaviridae/fisiologia; Tetraspanina 24/química; Tetraspanina 24/metabolismo; Tetraspanina 28/química; Tetraspanina 28/metabolismo; Tetraspanina 30/química; Tetraspanina 30/metabolismo; Tetraspaninas/química; Internalização do Vírus

Palavras-chave

cytomegalovirus; endocytosis; entry; papillomavirus; tetraspanins; trafficking

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Infecções por Citomegalovirus / Infecções por Papillomavirus / Tetraspaninas Limite: Humans Idioma: En Revista: Biochem Soc Trans Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google