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Epigenetic repression of miR-375 is the dominant mechanism for constitutive activation of the PDPK1/RPS6KA3 signalling axis in multiple myeloma.
Tatekawa, Shotaro; Chinen, Yoshiaki; Ri, Masaki; Narita, Tomoko; Shimura, Yuji; Matsumura-Kimoto, Yayoi; Tsukamoto, Taku; Kobayashi, Tsutomu; Kawata, Eri; Uoshima, Nobuhiko; Taki, Tomohiko; Taniwaki, Masafumi; Handa, Hiroshi; Iida, Shinsuke; Kuroda, Junya.
Afiliação
  • Tatekawa S; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Chinen Y; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Ri M; Department of Haematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
  • Narita T; Department of Haematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
  • Shimura Y; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Matsumura-Kimoto Y; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Tsukamoto T; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Kobayashi T; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Kawata E; Department of Haematology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
  • Uoshima N; Department of Haematology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
  • Taki T; Department of Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Taniwaki M; Department of Molecular Diagnostics and Therapeutics, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Handa H; Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan.
  • Iida S; Department of Haematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
  • Kuroda J; Division of Haematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Br J Haematol ; 178(4): 534-546, 2017 08.
Article em En | MEDLINE | ID: mdl-28439875
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases S6 Ribossômicas 90-kDa / MicroRNAs / Repressão Epigenética / Proteínas Quinases Dependentes de 3-Fosfoinositídeo / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Br J Haematol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases S6 Ribossômicas 90-kDa / MicroRNAs / Repressão Epigenética / Proteínas Quinases Dependentes de 3-Fosfoinositídeo / Mieloma Múltiplo Limite: Humans Idioma: En Revista: Br J Haematol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Japão