Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA-protein correlations at the level of single cells.

Kirschman, Jonathan L; Bhosle, Sushma; Vanover, Daryll; Blanchard, Emmeline L; Loomis, Kristin H; Zurla, Chiara; Murray, Kathryn; Lam, Blaine C; Santangelo, Philip J

Kirschman, Jonathan L; Bhosle, Sushma; Vanover, Daryll; Blanchard, Emmeline L; Loomis, Kristin H; Zurla, Chiara; Murray, Kathryn; Lam, Blaine C; Santangelo, Philip J.

Afiliação

Kirschman JL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Bhosle S; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Vanover D; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Blanchard EL; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Loomis KH; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Zurla C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Murray K; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Lam BC; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.
Santangelo PJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, UA Whitaker Building, 313 Ferst Drive, Atlanta, GA 30332, USA.

Nucleic Acids Res ; 45(12): e113, 2017 Jul 07.

Article em En | MEDLINE | ID: mdl-28449134

Assuntos

Endossomos/metabolismo; Imagem Óptica/métodos; RNA Mensageiro/farmacocinética; Análise de Célula Única/métodos; Coloração e Rotulagem/métodos; Animais; Transporte Biológico; Carbocianinas/química; Linhagem Celular; Grânulos Citoplasmáticos/metabolismo; Grânulos Citoplasmáticos/ultraestrutura; Fibroblastos/citologia; Fibroblastos/metabolismo; Corantes Fluorescentes/química; Proteínas de Fluorescência Verde/genética; Proteínas de Fluorescência Verde/metabolismo; Células HeLa; Humanos; Raios Infravermelhos; Injeções Intramusculares; Camundongos; Sondas Moleculares/química; Hibridização de Ácido Nucleico; RNA Mensageiro/química; RNA Mensageiro/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endossomos / Coloração e Rotulagem / RNA Mensageiro / Análise de Célula Única / Imagem Óptica Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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