Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains.

Popp, Christina; Hampe, Irene A I; Hertlein, Tobias; Ohlsen, Knut; Rogers, P David; Morschhäuser, Joachim

Popp, Christina; Hampe, Irene A I; Hertlein, Tobias; Ohlsen, Knut; Rogers, P David; Morschhäuser, Joachim.

Afiliação

Popp C; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Hampe IAI; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Hertlein T; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Ohlsen K; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Rogers PD; Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Morschhäuser J; Institute for Molecular Infection Biology, University of Würzburg, Würzburg, Germany joachim.morschhaeuser@uni-wuerzburg.de.

Antimicrob Agents Chemother ; 61(7)2017 07.

Article em En | MEDLINE | ID: mdl-28461316

Assuntos

Antifúngicos/farmacologia; Candida albicans/efeitos dos fármacos; Fluconazol/farmacologia; Candida albicans/genética; Candida albicans/metabolismo; Farmacorresistência Fúngica/genética; Ergosterol/metabolismo; Proteínas Fúngicas/genética; Proteínas Fúngicas/metabolismo; Regulação Fúngica da Expressão Gênica/genética; Mutação/genética

Palavras-chave

Candida albicans; drug resistance evolution; fitness costs; gain-of-function mutation; transcription factors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Candida albicans / Fluconazol / Antifúngicos Tipo de estudo: Prognostic_studies Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

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