Characterization of new functionalized calcium carbonate-polycaprolactone composite material for application in geometry-constrained drug release formulation development.

Wagner-Hattler, Leonie; Schoelkopf, Joachim; Huwyler, Jörg; Puchkov, Maxim

Wagner-Hattler, Leonie; Schoelkopf, Joachim; Huwyler, Jörg; Puchkov, Maxim.

Afiliação

Wagner-Hattler L; a Department of Pharmaceutical Sciences , University of Basel , Basel , Switzerland.
Schoelkopf J; b R&D Minerals and Surface Chemistry , Omya International AG , Oftringen , Switzerland.
Huwyler J; a Department of Pharmaceutical Sciences , University of Basel , Basel , Switzerland.
Puchkov M; a Department of Pharmaceutical Sciences , University of Basel , Basel , Switzerland.

Drug Dev Ind Pharm ; 43(10): 1669-1676, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28481735

Assuntos

Carbonato de Cálcio/química; Excipientes/química; Poliésteres/química; Comprimidos/química; Química Farmacêutica; Liberação Controlada de Fármacos; Excipientes/farmacocinética; Poliésteres/farmacocinética; Solubilidade; Comprimidos/farmacocinética

Palavras-chave

Mineral-polymer composite; TIC device; dry-coated tablet; elastoplastic deformation; functionalized calcium carbonate; geometrically modified release; polycaprolactone; tablet formulation

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Poliésteres / Comprimidos / Carbonato de Cálcio / Excipientes Idioma: En Revista: Drug Dev Ind Pharm Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google