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Covalent Enzyme Inhibition through Fluorosulfate Modification of a Noncatalytic Serine Residue.
Fadeyi, Olugbeminiyi O; Hoth, Lise R; Choi, Chulho; Feng, Xidong; Gopalsamy, Ariamala; Hett, Erik C; Kyne, Robert E; Robinson, Ralph P; Jones, Lyn H.
Afiliação
  • Fadeyi OO; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Hoth LR; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Choi C; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Feng X; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Gopalsamy A; Medicine Design, Pfizer Inc. , 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Hett EC; Medicine Design, Pfizer Inc. , 610 Main Street, Cambridge, Massachusetts 02139, United States.
  • Kyne RE; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Robinson RP; Medicine Design, Pfizer Inc. , Eastern Point Road, Groton, Connecticut 06340, United States.
  • Jones LH; Medicine Design, Pfizer Inc. , 610 Main Street, Cambridge, Massachusetts 02139, United States.
ACS Chem Biol ; 12(8): 2015-2020, 2017 08 18.
Article em En | MEDLINE | ID: mdl-28718624
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina / Ácidos Sulfúricos / Inibidores Enzimáticos / Fluoretos Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Serina / Ácidos Sulfúricos / Inibidores Enzimáticos / Fluoretos Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos