Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in the heart, skin, and lung.

Vermeulen, Zarha; Hervent, Anne-Sophie; Dugaucquier, Lindsey; Vandekerckhove, Leni; Rombouts, Miche; Beyens, Matthias; Schrijvers, Dorien M; De Meyer, Guido R Y; Maudsley, Stuart; De Keulenaer, Gilles W; Segers, Vincent F M

Vermeulen, Zarha; Hervent, Anne-Sophie; Dugaucquier, Lindsey; Vandekerckhove, Leni; Rombouts, Miche; Beyens, Matthias; Schrijvers, Dorien M; De Meyer, Guido R Y; Maudsley, Stuart; De Keulenaer, Gilles W; Segers, Vincent F M.

Afiliação

Vermeulen Z; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Hervent AS; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Dugaucquier L; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Vandekerckhove L; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Rombouts M; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Beyens M; Center of Medical Genetics, University of Antwerp, Antwerp, Belgium.
Schrijvers DM; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
De Meyer GRY; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Maudsley S; Department of Molecular Genetics, Flanders Interuniversity Institute for Biotechnology, University of Antwerp, Antwerp, Belgium.
De Keulenaer GW; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Segers VFM; Department of Cardiology, Middelheim Hospital, Antwerp, Belgium; and.

Am J Physiol Heart Circ Physiol ; 313(5): H934-H945, 2017 Nov 01.

Article em En | MEDLINE | ID: mdl-28822966

Assuntos

Macrófagos/metabolismo; Miocárdio/patologia; Neuregulina-1/metabolismo; Fibrose Pulmonar/patologia; Receptor ErbB-4/metabolismo; Transdução de Sinais; Pele/patologia; Animais; Cardiomiopatias/metabolismo; Cardiomiopatias/patologia; Ecocardiografia; Fibrose; Coração/diagnóstico por imagem; Hemodinâmica; Camundongos; Camundongos Endogâmicos C57BL; Miocardite/patologia; Miócitos Cardíacos/patologia; Fibrose Pulmonar/diagnóstico por imagem; Pele/diagnóstico por imagem

Palavras-chave

fibrosis; heart failure; macrophages; neuregulin-1; receptor tyrosine-protein kinase erbB-4

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Pele / Transdução de Sinais / Neuregulina-1 / Receptor ErbB-4 / Macrófagos / Miocárdio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Heart Circ Physiol Assunto da revista: CARDIOLOGIA / FISIOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Bélgica

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