Modulation of mitochondrial dysfunction and endoplasmic reticulum stress are key mechanisms for the wide-ranging actions of epoxy fatty acids and soluble epoxide hydrolase inhibitors.

Inceoglu, Bora; Bettaieb, Ahmed; Haj, Fawaz G; Gomes, Aldrin V; Hammock, Bruce D

Inceoglu, Bora; Bettaieb, Ahmed; Haj, Fawaz G; Gomes, Aldrin V; Hammock, Bruce D.

Afiliação

Inceoglu B; Department of Entomology and Nematology, UC Davis Comprehensive Cancer Center, University of California Davis, Davis, CA 95616, United States. Electronic address: abinceoglu@ucdavis.edu.
Bettaieb A; Department of Nutrition, The University of Tennessee, Knoxville, TN 37996-0840, United States; Graduate School of Genome Science and Technology, The University of Tennessee, Knoxville, TN 37996-0840, United States. Electronic address: abettaie@utk.edu.
Haj FG; Department of Nutrition, University of California Davis, CA 95616, United States; Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of California Davis, Sacramento, CA 95817, United States.
Gomes AV; Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, CA 95616, United States; Department of Physiology and Membrane Biology, University of California Davis, Davis, CA 95616, United States.
Hammock BD; Department of Entomology and Nematology, UC Davis Comprehensive Cancer Center, University of California Davis, Davis, CA 95616, United States.

Prostaglandins Other Lipid Mediat ; 133: 68-78, 2017 Nov.

Article em En | MEDLINE | ID: mdl-28847566

Assuntos

Estresse do Retículo Endoplasmático/efeitos dos fármacos; Inibidores Enzimáticos/farmacologia; Epóxido Hidrolases/antagonistas & inibidores; Epóxido Hidrolases/química; Ácidos Graxos/química; Ácidos Graxos/farmacologia; Mitocôndrias/efeitos dos fármacos; Animais; Epóxido Hidrolases/metabolismo; Humanos; Mitocôndrias/metabolismo; Solubilidade

Palavras-chave

Arachidonic acid; Endoplasmic reticulum stress; Epoxy fatty acids; Epoxydocosapentaenoic acid; Mitochondria; Soluble epoxide hydrolase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Epóxido Hidrolases / Ácidos Graxos / Estresse do Retículo Endoplasmático / Mitocôndrias Limite: Animals / Humans Idioma: En Revista: Prostaglandins Other Lipid Mediat Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2017 Tipo de documento: Article

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