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Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation.
Chen, Weiqiang; Foo, Suan-Sin; Zaid, Ali; Teng, Terk-Shin; Herrero, Lara J; Wolf, Stefan; Tharmarajah, Kothila; Vu, Luan D; van Vreden, Caryn; Taylor, Adam; Freitas, Joseph R; Li, Rachel W; Woodruff, Trent M; Gordon, Richard; Ojcius, David M; Nakaya, Helder I; Kanneganti, Thirumala-Devi; O'Neill, Luke A J; Robertson, Avril A B; King, Nicholas J; Suhrbier, Andreas; Cooper, Matthew A; Ng, Lisa F P; Mahalingam, Suresh.
Afiliação
  • Chen W; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Foo SS; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
  • Zaid A; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Teng TS; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA.
  • Herrero LJ; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Wolf S; Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Singapore, 138632, Singapore.
  • Tharmarajah K; Institute of Infection and Global Health, University of Liverpool, Liverpool, L69 7BE, UK.
  • Vu LD; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • van Vreden C; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Taylor A; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Freitas JR; Discipline of Pathology, Bosch Institute, School of Medical Sciences, Sydney Medical School, Charles Perkins Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
  • Li RW; Discipline of Pathology, Bosch Institute, School of Medical Sciences, Sydney Medical School, Charles Perkins Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
  • Woodruff TM; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Gordon R; Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University, Gold Coast, QLD, 4222, Australia.
  • Ojcius DM; The Medical School, The Australian National University, Acton, ACT, 2601, Australia.
  • Nakaya HI; Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Acton, ACT, 2601, Australia.
  • Kanneganti TD; School of Biomedical Science, The University of Queensland, Australia, St Lucia, QLD, 4072, Australia.
  • O'Neill LAJ; School of Biomedical Science, The University of Queensland, Australia, St Lucia, QLD, 4072, Australia.
  • Robertson AAB; Department of Biomedical Sciences, University of the Pacific, San Francisco, CA, 94103, USA.
  • King NJ; Department of Pathophysiology and Toxicology, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, CEP 05508-000, Brazil.
  • Suhrbier A; Department of Immunology, St Jude's Children's Hospital, Memphis, TN, 38105, USA.
  • Cooper MA; Trinity Biomedical Sciences Institute, Trinity College Dublin, The University of Dublin, College Green, Dublin, 2, Ireland.
  • Ng LFP; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Mahalingam S; Discipline of Pathology, Bosch Institute, School of Medical Sciences, Sydney Medical School, Charles Perkins Centre, University of Sydney, Camperdown, NSW, 2006, Australia.
Nat Microbiol ; 2(10): 1435-1445, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28848230
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Alphavirus / Inflamassomos / Febre de Chikungunya / Proteína 3 que Contém Domínio de Pirina da Família NLR / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Microbiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Alphavirus / Inflamassomos / Febre de Chikungunya / Proteína 3 que Contém Domínio de Pirina da Família NLR / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Microbiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Austrália