UbcD1 regulates Hedgehog signaling by directly modulating Ci ubiquitination and processing.

Pan, Chenyu; Xiong, Yue; Lv, Xiangdong; Xia, Yuanxin; Zhang, Shuo; Chen, Hao; Fan, Jialin; Wu, Wenqing; Liu, Feng; Wu, Hailong; Zhou, Zhaocai; Zhang, Lei; Zhao, Yun

Pan, Chenyu; Xiong, Yue; Lv, Xiangdong; Xia, Yuanxin; Zhang, Shuo; Chen, Hao; Fan, Jialin; Wu, Wenqing; Liu, Feng; Wu, Hailong; Zhou, Zhaocai; Zhang, Lei; Zhao, Yun.

Afiliação

Pan C; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xiong Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Lv X; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Xia Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhang S; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Chen H; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Fan J; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Wu W; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Liu F; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wu H; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhou Z; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zhang L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zhao Y; State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China.

EMBO Rep ; 18(11): 1922-1934, 2017 11.

Article em En | MEDLINE | ID: mdl-28887318

Assuntos

Proteínas de Drosophila/genética; Drosophila melanogaster/genética; Regulação da Expressão Gênica no Desenvolvimento; Proteínas Hedgehog/genética; Processamento de Proteína Pós-Traducional; Enzimas de Conjugação de Ubiquitina/genética; Peixe-Zebra/genética; Animais; Proteínas de Ciclo Celular/genética; Proteínas de Ciclo Celular/metabolismo; Sequência Conservada; Proteínas de Ligação a DNA/genética; Proteínas de Ligação a DNA/metabolismo; Proteínas de Drosophila/metabolismo; Drosophila melanogaster/crescimento & desenvolvimento; Drosophila melanogaster/metabolismo; Embrião não Mamífero; Proteínas Hedgehog/metabolismo; Discos Imaginais/crescimento & desenvolvimento; Discos Imaginais/metabolismo; Larva/genética; Larva/crescimento & desenvolvimento; Larva/metabolismo; Receptor Patched-2/genética; Receptor Patched-2/metabolismo; Poliubiquitina/genética; Poliubiquitina/metabolismo; Estabilidade Proteica; Proteólise; Transdução de Sinais; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo; Enzimas de Conjugação de Ubiquitina/metabolismo; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação; Peixe-Zebra/crescimento & desenvolvimento; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/genética; Proteínas de Peixe-Zebra/metabolismo

Palavras-chave

Drosophila; Ci; Hedgehog; UbcD1; ubiquitination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peixe-Zebra / Processamento de Proteína Pós-Traducional / Regulação da Expressão Gênica no Desenvolvimento / Proteínas de Drosophila / Enzimas de Conjugação de Ubiquitina / Drosophila melanogaster / Proteínas Hedgehog Idioma: En Revista: EMBO Rep Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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