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An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure.
Hallam, Dean; Collin, Joseph; Bojic, Sanja; Chichagova, Valeria; Buskin, Adriana; Xu, Yaobo; Lafage, Lucia; Otten, Elsje G; Anyfantis, George; Mellough, Carla; Przyborski, Stefan; Alharthi, Sameer; Korolchuk, Viktor; Lotery, Andrew; Saretzki, Gabriele; McKibbin, Martin; Armstrong, Lyle; Steel, David; Kavanagh, David; Lako, Majlinda.
Afiliação
  • Hallam D; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Collin J; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Bojic S; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Chichagova V; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Buskin A; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Xu Y; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Lafage L; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Otten EG; Campus for Ageing and Vitality, Institute for Cell and Molecular Biosciences and Institute for Ageing, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Anyfantis G; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Mellough C; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Przyborski S; Department of Biosciences, Durham University, Durham, United Kingdom.
  • Alharthi S; Princess Al Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Saudi Arabia.
  • Korolchuk V; Campus for Ageing and Vitality, Institute for Cell and Molecular Biosciences and Institute for Ageing, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • Lotery A; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Saretzki G; Campus for Ageing and Vitality, Institute for Cell and Molecular Biosciences and Institute for Ageing, Newcastle University, Newcastle upon Tyne, United Kingdom.
  • McKibbin M; Leeds Teaching Hospital NHS, Leeds, United Kingdom.
  • Armstrong L; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Steel D; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Kavanagh D; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
  • Lako M; Institute of Genetic Medicine, International Centre for Life, United Kingdom.
Stem Cells ; 35(11): 2305-2320, 2017 11.
Article em En | MEDLINE | ID: mdl-28913923
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Terapia Ultravioleta / Células-Tronco Pluripotentes Induzidas / Degeneração Macular Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Aged / Animals / Humans Idioma: En Revista: Stem Cells Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raios Ultravioleta / Terapia Ultravioleta / Células-Tronco Pluripotentes Induzidas / Degeneração Macular Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Aged / Animals / Humans Idioma: En Revista: Stem Cells Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido