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Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Bömeke, Katrin; Tiburcy, Malte; Fomin, Andrey; Luo, Xiaojing; Li, Wener; Fischer, Claudia; Özcelik, Cemil; Perrot, Andreas; Sossalla, Samuel; Haas, Jan; Vidal, Ramon Oliveira; Rebs, Sabine; Khadjeh, Sara; Meder, Benjamin; Bonn, Stefan; Linke, Wolfgang A; Zimmermann, Wolfram-Hubertus; Hasenfuss, Gerd; Guan, Kaomei.
Afiliação
  • Streckfuss-Bömeke K; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany.
  • Tiburcy M; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany; Institute of Pharmacology and Toxicology, Universitätsmedizin Göttingen, Germany.
  • Fomin A; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany; Department of Cardiovascular Physiology, Ruhr University Bochum, Germany.
  • Luo X; Institute of Pharmacology and Toxicology, Technische Universität Dresden, Germany.
  • Li W; Institute of Pharmacology and Toxicology, Technische Universität Dresden, Germany.
  • Fischer C; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany.
  • Özcelik C; Cardiovascular Genetics, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Germany; Medizinischen Klinik I Kardiologie, Gastroenterologie und Diabetologie, Knappschaftskrankenhaus Recklingshausen, Germany.
  • Perrot A; Cardiovascular Genetics, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Germany.
  • Sossalla S; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany; Department of Internal Medicine 2 - Cardiology, University Medical Center Regensburg, Germany.
  • Haas J; Department of Cardiology, University of Heidelberg, Germany; DZHK, Partner Site Heidelberg, Germany.
  • Vidal RO; German Center for Neurodegenerative Diseases, Göttingen and Tübingen, Germany.
  • Rebs S; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany.
  • Khadjeh S; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany.
  • Meder B; Department of Cardiology, University of Heidelberg, Germany; DZHK, Partner Site Heidelberg, Germany.
  • Bonn S; German Center for Neurodegenerative Diseases, Göttingen and Tübingen, Germany; Institute of Medical Systems Biology, Center for Molecular Neurobiology, University Clinic Hamburg-Eppendorf, Hamburg, Germany.
  • Linke WA; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany; Department of Cardiovascular Physiology, Ruhr University Bochum, Germany.
  • Zimmermann WH; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany; Institute of Pharmacology and Toxicology, Universitätsmedizin Göttingen, Germany.
  • Hasenfuss G; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Germany.
  • Guan K; Department of Cardiology and Pneumology, Universitätsmedizin Göttingen, Germany; Institute of Pharmacology and Toxicology, Technische Universität Dresden, Germany. Electronic address: kaomei.guan@tu-dresden.de.
J Mol Cell Cardiol ; 113: 9-21, 2017 12.
Article em En | MEDLINE | ID: mdl-28941705
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada / Proteínas de Ligação a RNA / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cardiomiopatia Dilatada / Proteínas de Ligação a RNA / Miócitos Cardíacos / Células-Tronco Pluripotentes Induzidas Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans Idioma: En Revista: J Mol Cell Cardiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha