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SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.
Damonte, Patrizia; Sociali, Giovanna; Parenti, Marco Daniele; Soncini, Debora; Bauer, Inga; Boero, Silvia; Grozio, Alessia; Holtey, Maria von; Piacente, Francesco; Becherini, Pamela; Sanguineti, Roberta; Salis, Annalisa; Damonte, Gianluca; Cea, Michele; Murone, Maximilien; Poggi, Alessandro; Nencioni, Alessio; Del Rio, Alberto; Bruzzone, Santina.
Afiliação
  • Damonte P; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Sociali G; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy.
  • Parenti MD; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy.
  • Soncini D; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Bauer I; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Boero S; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy; IRCCS Azienda Ospedaliera Universitaria San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Grozio A; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy.
  • Holtey MV; Debiopharm International S.A., Chemin Messidor 5-7, 1002 Lausanne, Switzerland; Roche Diagnostics International AG, Forrenstrasse 2, 6343 Rotkreuz, Switzerland.
  • Piacente F; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Becherini P; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Sanguineti R; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Salis A; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy.
  • Damonte G; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy.
  • Cea M; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy.
  • Murone M; Debiopharm International S.A., Chemin Messidor 5-7, 1002 Lausanne, Switzerland; Cellestia Biotech AG, Hochbergerstrasse 60C, 4057 Basel, Switzerland.
  • Poggi A; IRCCS Azienda Ospedaliera Universitaria San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy.
  • Nencioni A; Department of Internal Medicine, University of Genoa, V.le Benedetto XV 6, 16132 Genoa, Italy; IRCCS Azienda Ospedaliera Universitaria San Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genoa, Italy. Electronic address: alessio.nencioni@unige.it.
  • Del Rio A; Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129 Bologna, Italy; Innovamol Srls, Viale A. Corassori 24, 41124 Modena, Italy. Electronic address: alberto.delrio@gmail.com.
  • Bruzzone S; Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy. Electronic address: santina.bruzzone@unige.it.
Bioorg Med Chem ; 25(20): 5849-5858, 2017 10 15.
Article em En | MEDLINE | ID: mdl-28958848
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salicilatos / Sistemas de Liberação de Medicamentos / Sirtuínas / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salicilatos / Sistemas de Liberação de Medicamentos / Sirtuínas / Inibidores Enzimáticos Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Itália