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IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease.
Dambuza, Ivy M; He, Chang; Choi, Jin Kyeong; Yu, Cheng-Rong; Wang, Renxi; Mattapallil, Mary J; Wingfield, Paul T; Caspi, Rachel R; Egwuagu, Charles E.
Afiliação
  • Dambuza IM; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • He C; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Choi JK; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, 510060, China.
  • Yu CR; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Wang R; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Mattapallil MJ; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute (NEI), National Institutes of Health (NIH), Bethesda, MD, 20892, USA.
  • Wingfield PT; Laboratory of Immunology, Beijing Institute of Basic Medical Sciences, Beijing, 100850, China.
  • Caspi RR; Immunoregulation Section, Laboratory of Immunology, NEI, NIH, Bethesda, MD, 20892, USA.
  • Egwuagu CE; Protein Expression Laboratory, National Institute Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health, Bethesda, MD, 20814, USA.
Nat Commun ; 8(1): 719, 2017 09 28.
Article em En | MEDLINE | ID: mdl-28959012
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Interleucina-10 / Subunidade p35 da Interleucina-12 / Linfócitos B Reguladores Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Interleucina-10 / Subunidade p35 da Interleucina-12 / Linfócitos B Reguladores Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos