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An integrin antagonist (MK-0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model.
Zhou, Xiaoyan; Zhang, Ji; Haimbach, Robin; Zhu, Wei; Mayer-Ezell, Rosemary; Garcia-Calvo, Margarita; Smith, Elizabeth; Price, Olga; Kan, Yanqing; Zycband, Emanuel; Zhu, Yonghua; Hoek, Maarten; Cox, Jason M; Ma, Lijun; Kelley, David E; Pinto, Shirly.
Afiliação
  • Zhou X; Department of Pharmacology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Zhang J; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Haimbach R; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Zhu W; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Mayer-Ezell R; Department of Pharmacology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Garcia-Calvo M; Department of Pharmacology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Smith E; Department of Pharmacology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Price O; Department of Pharmacology, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Kan Y; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Zycband E; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Zhu Y; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Hoek M; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Cox JM; Department of Medicinal Chemistry, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Ma L; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Kelley DE; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
  • Pinto S; Department of Cardiometabolic Diseases, Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey, 07033.
Article em En | MEDLINE | ID: mdl-28971604

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propionatos / Marcadores Genéticos / Integrina alfaV / Nefropatias Diabéticas / Rim / Naftiridinas Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propionatos / Marcadores Genéticos / Integrina alfaV / Nefropatias Diabéticas / Rim / Naftiridinas Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Perspect Ano de publicação: 2017 Tipo de documento: Article