Sciatic neurosteatosis: Relationship with age, gender, obesity and height.
Eur Radiol
; 28(4): 1673-1680, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-29063256
ABSTRACT
AIM:
To evaluate inter-reader performance for cross-sectional area and fat quantification of bilateral sciatic nerves on MRI and assess correlations with anthropometrics.METHODS:
In this IRB-approved, HIPPA-compliant study, three readers performed a cross-sectional analysis of 3T lumbosacral plexus MRIs over an 18-month period. Image slices were evaluated at two levels (A and B). The sciatic nerve was outlined using a free hand region of interest tool on PACS. Proton-density fat fraction (FF) and cross-sectional areas were recorded. Inter-reader agreement was assessed using intra-class correlation coefficient (ICC). Spearman correlation coefficients were used for correlations with age, BMI and height and Wilcoxon rank sum test was used to assess gender differences.RESULTS:
A total of 67 patients were included in this study with male to female ratio of 11. Inter-reader agreement was good to excellent for FF measurements at both levels (ICC=0.71-0.90) and poor for sciatic nerve areas (ICC=0.08-0.27). Positive correlations of sciatic FF and area were seen with age (p value<0.05). Males had significantly higher sciatic intraneural fat than females (p<0.05).CONCLUSION:
Fat quantification MRI is highly reproducible with significant positive correlations of sciatic FF and area with age, which may have implications for MRI diagnosis of sciatic neuropathy. KEY POINTS ⢠MR proton density fat fraction is highly reproducible at multiple levels. ⢠Sciatic intraneural fat is positively correlated with increasing age (p < 0.05). ⢠Positive correlations exist between bilateral sciatic nerve areas and age (p < 0.05). ⢠Males had significantly higher sciatic intraneural fat than females (p < 0.05).Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Nervo Isquiático
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Imageamento por Ressonância Magnética
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Tecido Adiposo
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Neuropatia Ciática
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur Radiol
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos