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Quantitative Assessment of Drug Delivery to Tissues and Association with Phospholipidosis: A Case Study with Two Structurally Related Diamines in Development.
Loryan, Irena; Hoppe, Edmund; Hansen, Klaus; Held, Felix; Kless, Achim; Linz, Klaus; Marossek, Virginia; Nolte, Bert; Ratcliffe, Paul; Saunders, Derek; Terlinden, Rolf; Wegert, Anita; Welbers, André; Will, Olaf; Hammarlund-Udenaes, Margareta.
Afiliação
  • Loryan I; Translational PKPD Group, Department of Pharmaceutical Biosciences, Associate member of SciLifeLab, Uppsala University , 751 24 Uppsala, Sweden.
  • Hoppe E; Grünenthal GmbH , 52099 Aachen, Germany.
  • Hansen K; Grünenthal GmbH , 52099 Aachen, Germany.
  • Held F; Fraunhofer-Chalmers Centre, Chalmers Science Park , 412 88 Gothenburg, Sweden.
  • Kless A; Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg , 412 96 Gothenburg, Sweden.
  • Linz K; Grünenthal GmbH , 52099 Aachen, Germany.
  • Marossek V; Grünenthal GmbH , 52099 Aachen, Germany.
  • Nolte B; Grünenthal GmbH , 52099 Aachen, Germany.
  • Ratcliffe P; Grünenthal GmbH , 52099 Aachen, Germany.
  • Saunders D; Grünenthal GmbH , 52099 Aachen, Germany.
  • Terlinden R; Grünenthal GmbH , 52099 Aachen, Germany.
  • Wegert A; Grünenthal GmbH , 52099 Aachen, Germany.
  • Welbers A; Grünenthal GmbH , 52099 Aachen, Germany.
  • Will O; Grünenthal GmbH , 52099 Aachen, Germany.
  • Hammarlund-Udenaes M; Grünenthal GmbH , 52099 Aachen, Germany.
Mol Pharm ; 14(12): 4362-4373, 2017 12 04.
Article em En | MEDLINE | ID: mdl-29099189
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diaminas / Lipidoses / Modelos Biológicos Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diaminas / Lipidoses / Modelos Biológicos Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia