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Brain tumors associated with psychogenic non-epileptic seizures: Case series.
Garcia, Catherine R; Khan, Gulam Q; Morrow, Amy M; Yadav, Priyanka; Lightner, Donita D; Gilliam, Frank G; Villano, John L.
Afiliação
  • Garcia CR; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.
  • Khan GQ; Department of Neurology, University of Kentucky, Lexington, KY, United States.
  • Morrow AM; Department of Clinical Oncology Pharmacy, University of Kentucky, Lexington, KY, United States.
  • Yadav P; Department of Neurology, University of Kentucky, Lexington, KY, United States.
  • Lightner DD; Department of Neurology, University of Kentucky, Lexington, KY, United States.
  • Gilliam FG; Department of Neurology, University of Kentucky, Lexington, KY, United States.
  • Villano JL; Department of Medicine, University of Kentucky, Lexington, KY, United States; Department of Neurology, University of Kentucky, Lexington, KY, United States; Department of Neurosurgery, University of Kentucky, Lexington, KY, United States; Markey Cancer Center, University of Kentucky, Lexington, KY,
Clin Neurol Neurosurg ; 164: 53-56, 2018 01.
Article em En | MEDLINE | ID: mdl-29175723
OBJECTIVE: The association of psychogenic non-epileptic seizures (PNES) with primary or secondary brain tumors has not been well described in the literature. We aim to discuss their association, and their impact in brain tumor treatment. PATIENTS AND METHODS: We identified four patients retrospectively from our practice. The diagnosis of PNES was based on clinical suspicion and standard EEG, supplemented with video-EEG recording in 2 patients. RESULTS: The initial diagnosis of brain tumor was associated with a new onset seizure prior to diagnosis. The majority of the patients presented with ES followed by recurrent PNES during the course of their disease. Patients were treated with multiple anti-epileptic drugs, requiring frequent schedule adjustments. The preferred tumor treatment modality was chemotherapy, followed by surgical resection. The patients were offered psychological consultation achieving partial control of their events. These patients manifested recurrent disabling clinical events that required multiple medical consultations. None of these patients presented clinical evidence of tumor progression at the time of PNES presentation. CONCLUSION: A high index of suspicion and early psychological consultation referral will likely mitigate the quality of life impact of PNES in these patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Neoplasias Encefálicas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Neurol Neurosurg Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Neoplasias Encefálicas Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Neurol Neurosurg Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos