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Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.
Bao, Leyuan; Hannon, Clare; Cruz-Mignoni, Abimael; Ptchelkine, Denis; Sun, Mei-Yi; Miller, Ami; Bunjobpol, Wilawan; Quevedo, Camilo E; Derveni, Mariliza; Chambers, Jennifer; Simmons, Alison; Phillips, Simon E V; Rabbitts, Terence H.
Afiliação
  • Bao L; Weatherall Institute of Molecular Medicine, MRC Human Immunology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Hannon C; School of Clinical Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Rd, Cambridge, CB2 0SP, UK.
  • Cruz-Mignoni A; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Ptchelkine D; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0FA, UK.
  • Sun MY; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0FA, UK.
  • Miller A; Weatherall Institute of Molecular Medicine, MRC Human Immunology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Bunjobpol W; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Quevedo CE; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Derveni M; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Chambers J; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Simmons A; Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Phillips SEV; Weatherall Institute of Molecular Medicine, MRC Human Immunology Unit, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.
  • Rabbitts TH; Research Complex at Harwell, Rutherford Appleton Laboratory, Didcot, OX11 0FA, UK.
Sci Rep ; 7(1): 16869, 2017 12 04.
Article em En | MEDLINE | ID: mdl-29203900

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Integrase de HIV / Peptídeos e Proteínas de Sinalização Intercelular / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por HIV / Integrase de HIV / Peptídeos e Proteínas de Sinalização Intercelular / Anticorpos de Domínio Único Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido