Defined tetra-allelic gene disruption of the 4-coumarate:coenzyme A ligase 1 (Pv4CL1) gene by CRISPR/Cas9 in switchgrass results in lignin reduction and improved sugar release.

Park, Jong-Jin; Yoo, Chang Geun; Flanagan, Amy; Pu, Yunqiao; Debnath, Smriti; Ge, Yaxin; Ragauskas, Arthur J; Wang, Zeng-Yu

Park, Jong-Jin; Yoo, Chang Geun; Flanagan, Amy; Pu, Yunqiao; Debnath, Smriti; Ge, Yaxin; Ragauskas, Arthur J; Wang, Zeng-Yu.

Afiliação

Park JJ; Noble Research Institute, Ardmore, OK 73401 USA.
Yoo CG; BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Flanagan A; BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Pu Y; Joint Institute for Biological Sciences, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830 USA.
Debnath S; Noble Research Institute, Ardmore, OK 73401 USA.
Ge Y; BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Ragauskas AJ; BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN 37831 USA.
Wang ZY; Joint Institute for Biological Sciences, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830 USA.

Biotechnol Biofuels ; 10: 284, 2017.

Article em En | MEDLINE | ID: mdl-29213323

Palavras-chave

4-Coumarate:coenzyme A ligase; 4CL; Bioenergy; CRISPR/Cas9; Genome editing; Lignin biosynthesis; Panicum virgatum; Sugar release; Switchgrass

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biotechnol Biofuels Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biotechnol Biofuels Ano de publicação: 2017 Tipo de documento: Article