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A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Swinnen, Bart; Bento-Abreu, Andre; Gendron, Tania F; Boeynaems, Steven; Bogaert, Elke; Nuyts, Rik; Timmers, Mieke; Scheveneels, Wendy; Hersmus, Nicole; Wang, Jiou; Mizielinska, Sarah; Isaacs, Adrian M; Petrucelli, Leonard; Lemmens, Robin; Van Damme, Philip; Van Den Bosch, Ludo; Robberecht, Wim.
Afiliação
  • Swinnen B; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Bento-Abreu A; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Gendron TF; Department of Neurology, University Hospitals Leuven, 3000, Leuven, Belgium.
  • Boeynaems S; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Bogaert E; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Nuyts R; Department of Neuroscience, Mayo Clinic Florida, Jacksonville, FL, 32224, USA.
  • Timmers M; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Scheveneels W; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Hersmus N; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Wang J; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Mizielinska S; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Isaacs AM; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Petrucelli L; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Lemmens R; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Van Damme P; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
  • Van Den Bosch L; Laboratory of Neurobiology, Center for Brain & Disease Research, VIB, Campus Gasthuisberg O&N 4, Herestraat 49, PB 602, 3000, Leuven, Belgium.
  • Robberecht W; Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, 3000, Leuven, Belgium.
Acta Neuropathol ; 135(3): 427-443, 2018 03.
Article em En | MEDLINE | ID: mdl-29302778
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Proteína C9orf72 / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Proteína C9orf72 / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Acta Neuropathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Bélgica