The Hippo Signaling Pathway in the Regulation of Skeletal Muscle Mass and Function.
Exerc Sport Sci Rev
; 46(2): 92-96, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29346163
ABSTRACT
The Hippo signaling pathway regulates the activity of the proteins Yes-associated protein (Yap) and transcriptional co-activator with PDZ-binding motif (Taz) to control tissue growth in many different cell types. Previously, we demonstrated that Yap is a critical regulator of skeletal muscle mass. We hypothesize that alterations in Yap and Taz activity modulate the anabolic adaptations of skeletal muscle to resistance exercise.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transdução de Sinais
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Proteínas Serina-Treonina Quinases
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Músculo Esquelético
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Treinamento Resistido
Limite:
Humans
Idioma:
En
Revista:
Exerc Sport Sci Rev
Ano de publicação:
2018
Tipo de documento:
Article