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Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.
Yang, Zhengrong; Hildebrandt, Ellen; Jiang, Fan; Aleksandrov, Andrei A; Khazanov, Netaly; Zhou, Qingxian; An, Jianli; Mezzell, Andrew T; Xavier, Bala M; Ding, Haitao; Riordan, John R; Senderowitz, Hanoch; Kappes, John C; Brouillette, Christie G; Urbatsch, Ina L.
Afiliação
  • Yang Z; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Hildebrandt E; Department of Cell Biology and Biochemistry, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX 79430, USA.
  • Jiang F; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA.
  • Aleksandrov AA; Department of Biochemistry and Biophysics and Cystic Fibrosis Treatment and Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Khazanov N; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel.
  • Zhou Q; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL, USA.
  • An J; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL, USA.
  • Mezzell AT; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA.
  • Xavier BM; Department of Cell Biology and Biochemistry, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX 79430, USA.
  • Ding H; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA.
  • Riordan JR; Department of Biochemistry and Biophysics and Cystic Fibrosis Treatment and Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Senderowitz H; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel.
  • Kappes JC; Department of Medicine, University of Alabama at Birmingham, 701 19th Street South, Birmingham, AL 35294-0007, USA; Birmingham Veterans Affairs Medical Center, Research Service, Birmingham, AL 35233, USA.
  • Brouillette CG; Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: christie@uab.edu.
  • Urbatsch IL; Department of Cell Biology and Biochemistry, Center for Membrane Protein Research, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 6540, Lubbock, TX 79430, USA. Electronic address: ina.urbatsch@ttuhsc.edu.
Biochim Biophys Acta Biomembr ; 1860(5): 1193-1204, 2018 May.
Article em En | MEDLINE | ID: mdl-29425673
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulador de Condutância Transmembrana em Fibrose Cística / Domínios e Motivos de Interação entre Proteínas / Mutação / Nucleotídeos Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Biomembr Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulador de Condutância Transmembrana em Fibrose Cística / Domínios e Motivos de Interação entre Proteínas / Mutação / Nucleotídeos Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Biomembr Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos