An unexpected player in Gaucher disease: The multiple roles of complement in disease development.

Pandey, Manoj K; Grabowski, Gregory A; Köhl, Jörg

Pandey, Manoj K; Grabowski, Gregory A; Köhl, Jörg.

Afiliação

Pandey MK; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; The Department of Pediatrics of the University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA. Electronic address: manoj.pandey@cchmc.org.
Grabowski GA; Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; The Department of Pediatrics of the University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.
Köhl J; Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; The Department of Pediatrics of the University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA; Institute for Systemic Inflammation Research, University of Lübeck, 23562, Lübeck, Germany. Electronic address: joerg.koehl@uksh.de.

Semin Immunol ; 37: 30-42, 2018 06.

Article em En | MEDLINE | ID: mdl-29478824

Assuntos

Complemento C5a/metabolismo; Doença de Gaucher/imunologia; Glucosilceramidase/genética; Inflamação/imunologia; Doenças por Armazenamento dos Lisossomos/imunologia; Animais; Autoanticorpos/metabolismo; Doença de Gaucher/genética; Glucosilceramidas/metabolismo; Humanos; Receptor da Anafilatoxina C5a/metabolismo

Palavras-chave

Antibodies; Autoimmunity; C5a; C5a receptor; Gaucher disease; Immune complex

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complemento C5a / Doenças por Armazenamento dos Lisossomos / Doença de Gaucher / Glucosilceramidase / Inflamação Limite: Animals / Humans Idioma: En Revista: Semin Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google