Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis in Mice via a Toll-Like Receptor 4/p21-Activated Kinase 1 Cascade.

Wu, Yaxin; Wu, Jiao; Chen, Ting; Li, Qing; Peng, Wei; Li, Huan; Tang, Xiaowei; Fu, Xiangsheng

Wu, Yaxin; Wu, Jiao; Chen, Ting; Li, Qing; Peng, Wei; Li, Huan; Tang, Xiaowei; Fu, Xiangsheng.

Afiliação

Wu Y; Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China.
Wu J; Endoscopy Center, The Affiliated Hospital of Southwest Medical University, Street Taiping 25#, Luzhou, 646000, Sichuan, China.
Chen T; Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China.
Li Q; Endoscopy Center, The Affiliated Hospital of Southwest Medical University, Street Taiping 25#, Luzhou, 646000, Sichuan, China.
Peng W; Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China.
Li H; Endoscopy Center, The Affiliated Hospital of Southwest Medical University, Street Taiping 25#, Luzhou, 646000, Sichuan, China.
Tang X; Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, China.
Fu X; Endoscopy Center, The Affiliated Hospital of Southwest Medical University, Street Taiping 25#, Luzhou, 646000, Sichuan, China.

Dig Dis Sci ; 63(5): 1210-1218, 2018 05.

Article em En | MEDLINE | ID: mdl-29508166

Assuntos

Neoplasias Colorretais/microbiologia; Fusobacterium nucleatum; Receptor 4 Toll-Like/metabolismo; Quinases Ativadas por p21/metabolismo; Animais; Antibacterianos/farmacologia; Biomarcadores/metabolismo; Western Blotting; Neoplasias Colorretais/metabolismo; Neoplasias Colorretais/patologia; Fezes/microbiologia; Microbioma Gastrointestinal/efeitos dos fármacos; Imuno-Histoquímica; Hibridização in Situ Fluorescente; Mucosa Intestinal/efeitos dos fármacos; Mucosa Intestinal/metabolismo; Mucosa Intestinal/microbiologia; Mucosa Intestinal/patologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Distribuição Aleatória; Transdução de Sinais; beta Catenina/metabolismo

Palavras-chave

Colorectal cancer; Fusobacterium nucleatum; Toll-like receptor 4; p21-activated kinase 1; ß-Catenin signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Fusobacterium nucleatum / Receptor 4 Toll-Like / Quinases Ativadas por p21 Limite: Animals Idioma: En Revista: Dig Dis Sci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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