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Tetrahydrobiopterin treatment reduces brain L-Phe but only partially improves serotonin in hyperphenylalaninemic ENU1/2 mice.
Scherer, Tanja; Allegri, Gabriella; Sarkissian, Christineh N; Ying, Ming; Grisch-Chan, Hiu Man; Rassi, Anahita; Winn, Shelley R; Harding, Cary O; Martinez, Aurora; Thöny, Beat.
Afiliação
  • Scherer T; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland.
  • Allegri G; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland.
  • Sarkissian CN; Department of Biology, McGill University, Montreal, QC, H3A 1B1, Canada.
  • Ying M; Department of Biomedicine and K.G. Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.
  • Grisch-Chan HM; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland.
  • Rassi A; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland.
  • Winn SR; Department of Molecular and Medical Genetics, School of Medicine, Oregon Science & Health University, Portland, OR, USA.
  • Harding CO; Department of Molecular and Medical Genetics, School of Medicine, Oregon Science & Health University, Portland, OR, USA.
  • Martinez A; Department of Biomedicine and K.G. Jebsen Centre for Neuropsychiatric Disorders, University of Bergen, Bergen, Norway. aurora.martinez@uib.no.
  • Thöny B; Department of Pediatrics, Divisions of Metabolism and of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland. beat.thony@kispi.uzh.ch.
J Inherit Metab Dis ; 41(4): 709-718, 2018 07.
Article em En | MEDLINE | ID: mdl-29520738
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Biopterinas / Encéfalo / Serotonina Limite: Animals / Humans Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Biopterinas / Encéfalo / Serotonina Limite: Animals / Humans Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suíça