HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence.

Brandão, Fabiana; Esher, Shannon K; Ost, Kyla S; Pianalto, Kaila; Nichols, Connie B; Fernandes, Larissa; Bocca, Anamélia L; Poças-Fonseca, Marcio José; Alspaugh, J Andrew

Brandão, Fabiana; Esher, Shannon K; Ost, Kyla S; Pianalto, Kaila; Nichols, Connie B; Fernandes, Larissa; Bocca, Anamélia L; Poças-Fonseca, Marcio José; Alspaugh, J Andrew.

Afiliação

Brandão F; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
Esher SK; Department of Medicine/Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Ost KS; Department of Medicine/Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Pianalto K; Department of Medicine/Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Nichols CB; Department of Medicine/Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA.
Fernandes L; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
Bocca AL; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
Poças-Fonseca MJ; Department of Cell Biology, Institute of Biological Sciences, University of Brasília, Brasília, Brazil.
Alspaugh JA; Department of Medicine/Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. andrew.alspaugh@duke.edu.

Sci Rep ; 8(1): 5209, 2018 03 26.

Article em En | MEDLINE | ID: mdl-29581526

Assuntos

Criptococose/genética; Cryptococcus neoformans/enzimologia; Histona Desacetilases/genética; Virulência/genética; Animais; Parede Celular; Criptococose/enzimologia; Criptococose/microbiologia; Cryptococcus neoformans/patogenicidade; Modelos Animais de Doenças; Regulação Enzimológica da Expressão Gênica/genética; Genoma Fúngico/genética; Histona Desacetilases/classificação; Humanos; Macrófagos/microbiologia; Macrófagos/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Virulência / Criptococose / Cryptococcus neoformans / Histona Desacetilases Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil

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