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A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial.
Greulich, Timm; Hohlfeld, Jens M; Neuser, Petra; Lueer, Katrin; Klemmer, Andreas; Schade-Brittinger, Carmen; Harnisch, Susanne; Garn, Holger; Renz, Harald; Homburg, Ursula; Renz, Jonas; Kirsten, Anne; Pedersen, Frauke; Müller, Meike; Vogelmeier, Claus F; Watz, Henrik.
Afiliação
  • Greulich T; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps-University, Member of the German Centre for Lung Research (DZL), Marburg, Germany. greulich@med.uni-marburg.de.
  • Hohlfeld JM; Department of Respiratory Medicine, Hannover Medical School, Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Centre for Lung Research (DZL), Hannover, Germany.
  • Neuser P; Coordinating Center for Clinical Trials, Member of the German Centre for Lung Research (DZL), Philipps-University, Marburg, Germany.
  • Lueer K; Department of Respiratory Medicine, Hannover Medical School, Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Centre for Lung Research (DZL), Hannover, Germany.
  • Klemmer A; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps-University, Member of the German Centre for Lung Research (DZL), Marburg, Germany.
  • Schade-Brittinger C; Coordinating Center for Clinical Trials, Member of the German Centre for Lung Research (DZL), Philipps-University, Marburg, Germany.
  • Harnisch S; Coordinating Center for Clinical Trials, Member of the German Centre for Lung Research (DZL), Philipps-University, Marburg, Germany.
  • Garn H; Department of Medicine, Institute of Laboratory Medicine and Pathobiochemistry - Molecular Diagnostics, Member of the German Centre for Lung Research (DZL), Philipps-University, Marburg, Germany.
  • Renz H; Department of Medicine, Institute of Laboratory Medicine and Pathobiochemistry - Molecular Diagnostics, Member of the German Centre for Lung Research (DZL), Philipps-University, Marburg, Germany.
  • Homburg U; Sterna Biologicals GmbH & Co. KG, Marburg, Germany.
  • Renz J; Sterna Biologicals GmbH & Co. KG, Marburg, Germany.
  • Kirsten A; Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Centre for Lung Research (DZL), Grosshansdorf, Germany.
  • Pedersen F; Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Centre for Lung Research (DZL), Grosshansdorf, Germany.
  • Müller M; Department of Respiratory Medicine, Hannover Medical School, Fraunhofer Institute for Toxicology and Experimental Medicine, Member of the German Centre for Lung Research (DZL), Hannover, Germany.
  • Vogelmeier CF; Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Centre Giessen and Marburg, Philipps-University, Member of the German Centre for Lung Research (DZL), Marburg, Germany.
  • Watz H; Pulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North (ARCN), Member of the German Centre for Lung Research (DZL), Grosshansdorf, Germany.
Respir Res ; 19(1): 55, 2018 04 04.
Article em En | MEDLINE | ID: mdl-29615049
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Eosinofilia Pulmonar / Escarro / DNA Catalítico / Doença Pulmonar Obstrutiva Crônica / Eosinófilos / Fator de Transcrição GATA3 Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Eosinofilia Pulmonar / Escarro / DNA Catalítico / Doença Pulmonar Obstrutiva Crônica / Eosinófilos / Fator de Transcrição GATA3 Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha