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Collagen type I induces EGFR-TKI resistance in EGFR-mutated cancer cells by mTOR activation through Akt-independent pathway.
Yamazaki, Shota; Higuchi, Youichi; Ishibashi, Masayuki; Hashimoto, Hiroko; Yasunaga, Masahiro; Matsumura, Yasuhiro; Tsuchihara, Katsuya; Tsuboi, Masahiro; Goto, Koichi; Ochiai, Atsushi; Ishii, Genichiro.
Afiliação
  • Yamazaki S; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.
  • Higuchi Y; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
  • Ishibashi M; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.
  • Hashimoto H; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
  • Yasunaga M; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
  • Matsumura Y; Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
  • Tsuchihara K; Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
  • Tsuboi M; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.
  • Goto K; Division of Developmental Therapeutics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
  • Ochiai A; Laboratory of Cancer Biology, Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.
  • Ishii G; Division of Developmental Therapeutics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, Japan.
Cancer Sci ; 109(6): 2063-2073, 2018 Jun.
Article em En | MEDLINE | ID: mdl-29701925
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colágeno Tipo I / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Receptores ErbB / Neoplasias Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Sci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colágeno Tipo I / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-akt / Serina-Treonina Quinases TOR / Receptores ErbB / Neoplasias Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Sci Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão