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The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner.
Jiang, Minqing; Rao, Rohit; Wang, Jincheng; Wang, Jiajia; Xu, Lingli; Wu, Lai Man; Chan, Jonah R; Wang, Huimin; Lu, Q Richard.
Afiliação
  • Jiang M; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Rao R; The Institute of Cognitive Neuroscience, East China Normal University, Shanghai, China.
  • Wang J; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Wang J; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Xu L; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Wu LM; Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai, China.
  • Chan JR; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Wang H; Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio.
  • Lu QR; Department of Neurology and Programs in Biomedical and Neurosciences, University of California, San Francisco, California.
Glia ; 66(9): 1947-1959, 2018 09.
Article em En | MEDLINE | ID: mdl-29722913
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Schwann / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Proliferação de Células / Serina-Treonina Quinases TOR / Proteína 1 do Complexo Esclerose Tuberosa / Homeostase Limite: Animals Idioma: En Revista: Glia Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células de Schwann / Proteínas Proto-Oncogênicas / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Proliferação de Células / Serina-Treonina Quinases TOR / Proteína 1 do Complexo Esclerose Tuberosa / Homeostase Limite: Animals Idioma: En Revista: Glia Assunto da revista: NEUROLOGIA Ano de publicação: 2018 Tipo de documento: Article