Proteomic definition of human mucosal-associated invariant T cells determines their unique molecular effector phenotype.

Bulitta, Björn; Zuschratter, Werner; Bernal, Isabel; Bruder, Dunja; Klawonn, Frank; von Bergen, Martin; Garritsen, Henrikus Stephanus Paulus; Jänsch, Lothar

Proteomic definition of human mucosal-associated invariant T cells determines their unique molecular effector phenotype.

Bulitta, Björn; Zuschratter, Werner; Bernal, Isabel; Bruder, Dunja; Klawonn, Frank; von Bergen, Martin; Garritsen, Henrikus Stephanus Paulus; Jänsch, Lothar.

Afiliação

Bulitta B; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Zuschratter W; Special Lab Electron and Laserscanning Microscopy, Leibniz Institute for Neurobiology, Magdeburg, Germany.
Bernal I; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Bruder D; Institute of Medical Microbiology and Hospital Hygiene, University Hospital Magdeburg, Magdeburg, Germany.
Klawonn F; Institute of Medical Microbiology and Hospital Hygiene, University Hospital Magdeburg, Magdeburg, Germany.
von Bergen M; Immune Regulation, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Garritsen HSP; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Jänsch L; Department of Computer Science, Ostfalia University of Applied Sciences, Wolfenbüttel, Germany.

Eur J Immunol ; 48(8): 1336-1349, 2018 08.

Article em En | MEDLINE | ID: mdl-29749611

Assuntos

Linfócitos T CD8-Positivos/imunologia; Exocitose/fisiologia; Células Matadoras Naturais/imunologia; Células T Invariantes Associadas à Mucosa/imunologia; Proteoma/análise; Biomarcadores/análise; Células Cultivadas; Dipeptidil Peptidase 4/metabolismo; Proteína-1 Reguladora de Fusão/metabolismo; Granzimas/metabolismo; Humanos; L-Aminoácido Oxidase/metabolismo; Proteína 1 de Membrana Associada ao Lisossomo/metabolismo; Espectrometria de Massas; Proteômica

Palavras-chave

CD8 T cells; Effector proteins; Immunological synapse; MAIT cells; Proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Linfócitos T CD8-Positivos / Proteoma / Exocitose / Células T Invariantes Associadas à Mucosa Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Eur J Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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