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Simultaneous population pharmacokinetic modelling of plasma and intracellular PBMC miltefosine concentrations in New World cutaneous leishmaniasis and exploration of exposure-response relationships.
Kip, Anke E; Castro, María Del Mar; Gomez, Maria Adelaida; Cossio, Alexandra; Schellens, Jan H M; Beijnen, Jos H; Saravia, Nancy Gore; Dorlo, Thomas P C.
Afiliação
  • Kip AE; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Castro MDM; Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Colombia.
  • Gomez MA; Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Colombia.
  • Cossio A; Centro Internacional de Entrenamiento e Investigaciones Medicas (CIDEIM), Cali, Colombia.
  • Schellens JHM; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
  • Beijnen JH; Department of Clinical Pharmacology, Antoni van Leeuwenhoek Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Saravia NG; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek Hospital/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Dorlo TPC; Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Utrecht, The Netherlands.
J Antimicrob Chemother ; 73(8): 2104-2111, 2018 08 01.
Article em En | MEDLINE | ID: mdl-29757380

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilcolina / Leishmaniose Cutânea Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Child / Child, preschool / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Colombia Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilcolina / Leishmaniose Cutânea Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Child / Child, preschool / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Colombia Idioma: En Revista: J Antimicrob Chemother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda