Obesity and Migraine: Effect Modification by Gender and Perceived Stress.
Neuroepidemiology
; 51(1-2): 25-32, 2018.
Article
em En
| MEDLINE
| ID: mdl-29843127
ABSTRACT
BACKGROUND:
The association between obesity and migraine has been established; however, it is unclear whether it varies by perceived stress within each gender.METHODS:
This cross-sectional study used data from the ongoing NutriNet-Santé e-cohort with enrollees from the general population. Anthropometric and migraine data were provided via self-report questionnaires (2013-2016). Migraine was defined using established criteria. Perceived stress was assessed with Cohen's Perceived Stress Scale-10. Associations were estimated via gender- and stress-stratified multivariable polytomous logistic regression models.RESULTS:
Among 32,835 participants with complete data (75% women; mean age = 51.9 ± 13.8 years), 34% reported no headache, 44% non-migraine headache, and 22% migraine with or without aura during one's lifetime. In these groups, obesity was present in 8.6, 9.9, and 11.6%, respectively. Stress was a significant moderator of the obesity-migraine association only among women. The largest significant adjusted odds ratio (aOR) was found between obesity and migraine in women with high stress (aOR 1.61, 95% CI 1.35-1.91).CONCLUSIONS:
We found support for gender- and stress-dependent associations between obesity and migraine using a large, heterogeneous adult sample. This underscores the need for evidence-based strategies for weight loss and stress reduction for female migraineurs.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estresse Psicológico
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Índice de Massa Corporal
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Transtornos de Enxaqueca
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Obesidade
Tipo de estudo:
Etiology_studies
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Observational_studies
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Prevalence_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Neuroepidemiology
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
França