Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells.

Xin, Yan; Wan, Bin; Yang, Yu; Cui, Xue-Jing; Xie, Yi-Chun; Guo, Liang-Hong

Xin, Yan; Wan, Bin; Yang, Yu; Cui, Xue-Jing; Xie, Yi-Chun; Guo, Liang-Hong.

Afiliação

Xin Y; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, P.O. Box 2871, Beijing, 100085, People's Republic of China.
Wan B; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China.
Yang Y; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, P.O. Box 2871, Beijing, 100085, People's Republic of China. binwan@rcees.ac.cn.
Cui XJ; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. binwan@rcees.ac.cn.
Xie YC; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, P.O. Box 2871, Beijing, 100085, People's Republic of China.
Guo LH; State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, P.O. Box 2871, Beijing, 100085, People's Republic of China.

Arch Toxicol ; 92(10): 3131-3147, 2018 10.

Article em En | MEDLINE | ID: mdl-30022264

Assuntos

Autofagia/efeitos dos fármacos; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Fluorocarbonos/toxicidade; Mitocôndrias/efeitos dos fármacos; Células A549; Autofagia/fisiologia; Caprilatos/química; Caprilatos/toxicidade; Sobrevivência Celular/efeitos dos fármacos; Ácidos Decanoicos/química; Ácidos Decanoicos/toxicidade; Ácidos Graxos; Fluorocarbonos/química; Humanos; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Mitocôndrias/metabolismo; Mitocôndrias/patologia; Mitofagia/efeitos dos fármacos; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

ER-phagy; Lung toxicity; Mitophagy; PFAAs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Estresse do Retículo Endoplasmático / Fluorocarbonos / Mitocôndrias Limite: Humans Idioma: En Revista: Arch Toxicol Ano de publicação: 2018 Tipo de documento: Article

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