Accurate Titration of Infectious AAV Particles Requires Measurement of Biologically Active Vector Genomes and Suitable Controls.

François, Achille; Bouzelha, Mohammed; Lecomte, Emilie; Broucque, Frédéric; Penaud-Budloo, Magalie; Adjali, Oumeya; Moullier, Philippe; Blouin, Véronique; Ayuso, Eduard

François, Achille; Bouzelha, Mohammed; Lecomte, Emilie; Broucque, Frédéric; Penaud-Budloo, Magalie; Adjali, Oumeya; Moullier, Philippe; Blouin, Véronique; Ayuso, Eduard.

Afiliação

François A; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Bouzelha M; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Lecomte E; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Broucque F; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Penaud-Budloo M; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Adjali O; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Moullier P; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Blouin V; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.
Ayuso E; INSERM UMR1089, University of Nantes, Centre Hospitalier Universitaire, Nantes, France.

Mol Ther Methods Clin Dev ; 10: 223-236, 2018 Sep 21.

Article em En | MEDLINE | ID: mdl-30112419

Palavras-chave

AAV vectors; gene therapy; infectivity; quality control; titration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França

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